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Today's date is Thursday, October 29, 2020
Student Events
 May 2012
Tuesday 29
13:00 - SEMINAR - The regulation of brain temperature in mammals and factors affecting the daily rhythm of body temperature. : School of Anatomy, Physiology & Human Biology Seminar Series Website | More Information
The Seminar: The seminar will focus on the two main areas of research conducted in the comparative and thermal physiology lab; the mechanism and use of selective brain cooling in some animals, and the variation in the circadian rhythm of core body temperature (and what it might mean). When it was first discovered selective brain cooling was promulgated as an adaptation that protected a thermally vulnerable brain during heat exposure. Over the last few years we have shown that this does not seem to be the case because the only time free-living animals get very hot is during exercise, and during exercise selective brain cooling is not activated. Rather the mechanism seems to have a direct effect on water use for thermoregulation in hot conditions, via panting and sweating. Thus the selective importance of the mechanism is quite subtle and is related to water economy rather than to thermoregulation per se.

Traditionally it is accepted that small mammals have all the machinery required to be homeothermic (maintain a constant, high body temperature), but for reasons of energy economy occasionally abandon homeothermy and enter torpor or hibernation. Large mammals are considered to be strict homeotherms. Data we have collected from a range of ‘large’ mammals suggests that energy balance can effect homeothermy in them too, suggesting that thermoregulatory patterns in animals form a continuum rather than a strict dichotomy. We use these data to show, though, that a better homeotherm performs better on several measures of animal performance, including growth and reproduction. Whether this is a cause and effect relationship remains to be established.

The Speaker: Shane Maloney is a Professor in the School of Anatomy, Physiology, and Human Biology at the University of Western Australia. He did his PhD at the University of New South Wales on thermal biology of the emu followed by a post-doctoral fellowship in the Brain Function Research Unit at the University of the Witwatersrand, where he focussed on brain temperature regulation in mammals. Since 1999 he has been at the University of Western Australia where his research centres on environmental physiology in man and other animals, with a focus on heat balance, energy use, and the mechanisms of thermoregulation.

13:00 - TALK - Careers Centre: Deloitte Dream Team Competition 2012 Information Session : Deloitte Dream Team Competition 2012 Information Session information session Website | More Information
Find out more about the Deloitte Dream Team, an annual inter-university competition where students compete in university teams to solve realistic business problems and scenarios.Book through Careerhub.

16:00 - EVENT - Same-Sex Relations: A First Century CE Perspective : Three Universities Lecture Series Website | More Information
The next lecture in the ‘Three Universities Lecture Series’ is……

Same-Sex Relations: A First Century CE Perspective, Emeritus Professor Bill Loader

Tuesday 29th May, 4–6pm at Murdoch University, Education and Humanities Building, Room EH1.001. Use Car Park 4 or 5, off South St. (bring coins for ticket machine).

Emeritus Professor Bill Loader recently completed a five year Australian Research Council Professorial Fellowship Project (2005-2010) on Attitudes towards Sexuality in Judaism and Christianity in the Hellenistic Greco-Roman Era. Professor Loader has written numerous books on sexuality in the New Testament period. He is a Minister of the Uniting Church in Australia.

The 'three universities lecture series' aims to share knowledge and build relationships across three Western Australian universities which share an interest in religious studies and/or theology (Murdoch; Notre Dame; UWA). The lectures will be of particular interest to academics and students in the fields of philosophy, religious studies or theology and may also appeal to members of the broader community.

Bill will speak for up to an hour followed by questions and snacks/drinks.

For catering purposes, please RSVP to [email protected] Phone: 6488 4762

Wednesday 30
13:00 - SEMINAR - Tumor-specific Regulation of MnSOD: Towards targeted "oxidation therapy" in estrogen negative breast cancer : School of Anatomy, Physiology & Human Biology Seminar Series Website | More Information
The Seminar: Compelling evidence suggests that cancer cells are generally under reactive oxygen species (ROS) stress. As mitochondria respiration is the main source of ROS generation in the cells, MnSOD is of prime importance in maintaining the tumor cellular ROS balance. It has recently been reported that generation of ROS is closely involved in PPAR ligand–induced apoptosis. However, the mechanism by which these ligands induce ROS generation remains unknown. We report the identification of human MnSOD as a PPAR target gene and that activation by PPAR agonists led to downregulation of MnSOD gene expression in vitro and in vivo xenograft model. Futhermore, histopathologic analysis of breast cancer biopsies obtained from patients treated with synthetic PPAR agonists also showed MnSOD repression. Repression of MnSOD expression was accompanied with increase in intracellular superoxide production in breast cancer cells. Suppression of MnSOD levels by small-interfering RNA or activation of PPAR in breast cancer cells increased oxidative stress and enhanced chemo-sensitivity to ROS-inducing drugs such as docetaxel and doxorubicin. Importantly, normal breast cells were completely refractory to these effects. Together, our data not only identifies MnSOD as a novel PPAR target but also provides a molecular mechanism for ROS-manipulation therapy through the intelligent use of PPAR ligands in combination with ROS-inducing drugs to preferentially kill cancer cells.

The Speaker: Dr. Alan Prem Kumar earned his Ph.D. from University of North Texas, USA. From his Ph.D. work, he discovered a novel regulatory protein, PyrR for the pyrimidine biosynthetic pathway in Pseudomonas. Because pyrimidine biosynthesis is an essential step in the progression of secondary Pseudomonas infections, PyrR presents an attractive anti-pseudomonal drug target. Dr. Kumar then pursued Postdoctoral training in Cancer Research at Sidney Kimmel Cancer Center, California, USA. He was awarded a Postdoctoral Fellowship for his work on the role of nuclear receptors in the transcriptional regulation of human myeloperoxidase, a leukocyte enzyme implicated as causative agent in atherosclerosis and Alzheimer’s disease. Dr. Kumar relocated back to Singapore to join the Faculty of Medicine, National University of Singapore as an independent Principal Investigator to continue on his expertise on nuclear receptor and cancer biology. His current research interest includes the role of nuclear receptors involved in the regulation of target genes and to elucidate mechanism and associated signal pathways. Another area of interest is to have a greater understanding of these nuclear receptors – aimed at developing newer selective PPAR gamma modulators, drugs with more potent activity and less toxicity. Towards this end, Dr Kumar identified a series of 21 structurally new PPAR gamma activators by computer-aided drug design using a combination of ligand-based and structure-based approaches. In collaboration with GenoMed, Inc, USA, he has recently identified a new tyrosine kinase involved in the progression of ovarian, breast, and prostate cancers. Inhibitors were developed against this kinase using computer-aided drug design. His goal is to use these drugs to demonstrate its effectiveness in a variety of cancer cell lines, mouse xenograft, with intent to clinical trials here in Singapore. Over the years, Dr. Kumar and his laboratory have forged relationships with scientists in cancer research and with cancer advocacy groups in Singapore.

Host: E/Prof Dharmarajan - PH) 6488 2981

13:00 - TALK - Careers Centre: Employer Talk - Birman & Ride Law Cadetships 2012 : Birman & Ride law cadetships: We invite applications from law undergraduates (at any stage of their degrees) interested in a litigation or commercial career with a boutique city law firm. Website | More Information
Applications must be made via our website www.cadetships.birmanride.com.au Closing date - Friday 15 June 2012 Attend our free on-campus information session on Wednesday 30 May 2012 at 1pm at UWA Social Sciences Lecture Room 1 (SSLR1). Book via Careerhub.

16:00 - SEMINAR - “Epigenomics of the dynamic mammalian DNA methylome” Website | More Information
My research focuses on the role of epigenomic modifications in genome organization and transcription in complex eukaryotic organisms. After receiving my Ph.D. from the University of Western Australia, I joined Joseph Ecker's laboratory at The Salk Institute for Biological Studies in 2006. I developed methodologies for utilizing high-throughput DNA sequencing technologies to achieve base-resolution mapping of DNA methylation throughout plant and mammalian genomes. Integration of these reference methylation maps with transcriptome and chromatin modification profiles has yielded new insights into the composition and function of DNA methylation in plants, people, and pluripotency. My ongoing research is focused upon how these complex epigenomic patterns are established and altered, and how they affect the readout of underlying genetic information.
Thursday 31
15:00 - EVENT - Archaeology Seminar: Professor Alistair Paterson : A millennium of cultural contact Website | More Information
This seminar reviews the process of cultural contact over the last millennium throughout the world. Traversing the globe from crossing the North Atlantic at AD1,000, and opening trade routes across Asia by the 18th century, Europeans had established colonies and trading posts in the far reaches of Australia and Oceania.

The wide variations in exploration, conquests and colonisation are discussed using archaeological case studies of the material culture and history of the indigenous peoples of all continents as they resisted, accommodated, repelled or were conquered by the newcomers.

Join us for this final session in the Archaeology Seminar Series for First Semester 2012.

 June 2012
Tuesday 05
13:00 - SEMINAR - Lung injury and fibrosis: can stem cells deliver regeneration? : School of Anatomy, Physiology & Human Biology Seminar Series More Information
The Seminar: The lung is a remarkable organ with gas exchange and vital immune defence roles accomplished in a branching network of airways and about 200 million alveoli. It is also an extremely dynamic tissue with rapid turnover of lung cells and their surrounding matrix which may explain the ability of new lung tissue regeneration in experimental models of lung growth. Chronic lung diseases such as pulmonary fibrosis and chronic obstructive pulmonary disease are a major cause of illness and an enormous burden on world health systems. Treatment for these diseases is inadequate with patients unresponsive to most current therapies and, despite large programmes in drug discovery, no agents are emerging that can cure or reverse chronic lung diseases. There is hope that cell therapeutic approaches with the regeneration of new lung tissue might be achievable and initial reports using progenitor cells derived from the bone marrow suggest that this approach may ameliorate animal models of lung disease. The mechanism for this action is uncertain but likely depends on paracrine pathways rather than cell engraftment. This presentation reviews some of the milestones in pulmonary fibrosis research and presents data suggesting keratinocyte growth factor delivery in a transgene expressed by stem cells may be effective in preventing animal models of lung fibrosis.

The Speaker: Professor Laurent is currently the Head of the Research Department of Internal Medicine and the Director of the Centre for Respiratory Research at University College London. He directs a team of scientists and physicians conducting research into basic aspects of inflammation and tissue repair and has published over 200 articles in international journals of biomedical research. He was recently awarded the European Respiratory Societies Presidential Award for his contribution to lung science and is currently its head of Science. He is the Editor-in-Chief of the International Journal of Biochemistry and Cell Biology and has edited several books including a four volume Encyclopaedia of Respiratory Medicine. He is a Fellow of the Academy of Medical Sciences and Past- President of the British Association for Lung Research. In June 2012 he takes up a post at the University of Western Australia directing its newly formed Centre for Cell Therapies and Regenerative Medicine
Friday 08
10:00 - SEMINAR - “Investigating the kidney: morphogenesis to regeneration” Website | More Information
Melissa Little is a graduate of the University of Queensland having completed a PhD on the genetic basis of childhood cancer at the Queensland Institute of Medical Research. She continued this work as an Endeavour Fellow and the MRC Human Genetics Unit in Edinburgh before returning to the Centre for Molecular and Cellular Biology in 1992. Her molecular characterisation of the tumor suppressor WT1 broadened her field of interest to the molecular basis of normal urogenital development which led to a systems based analysis of gene expression. This has resulted in the most comprehensive temporo-spatial analysis of gene expression performed in any organ system. Currently an NHMRC Principal Research Fellow and Deputy Division Head, Melissa has been a laboratory head since 1995. Her research focus on the kidney has extended from development to disease, repair and regeneration where she has pioneered studies into potential cellular therapies for kidney disease.

12:30 - TALK - Postgraduate Course Guide Feedback Forum : Discussion of the current information available for prospective domestic postgraduate students at UWA More Information
The newly formed UWA Postgraduate Admissions Centre is looking for ways to improve the prospective UWA postgraduate student experience.

We’d love to get your thoughts and feedback on the current domestic postgraduate student course guide with the view to improving the content and layout for future editions.

A feedback forum will be held on Friday 8 June from 12.30pm - 1.30pm in Social Sciences Seminar Room G.210.

Coffee, tea and biscuits provided, or feel free to bring your lunch.

If you’d like to join the conversation, please RSVP to [email protected] by Wednesday 6 June.

If you’re keen to be involved but can’t make the forum, please send an email anyway so we can make other arrangements.
Wednesday 13
9:00 - COURSE - Course on genomic analysis using R More Information
Cedric Gondro is a statistical geneticist from the University of New England with extensive experience in analyzing and publishing data from various genomic platforms. He will be running a 3-day course on genomic analysis using the programming environment R. The course will be suitable for researchers undertaking genetic and expression profiling projects on different organisms. The course will comprise a series of lectures and hands-on practicals on the basics of programming in R, analysis of genome wide association and microarray data, and how to explore and utilise biological information from public databases. All course materials will be provided before commencement. Cost: Academic and post-doctoral scientists $150; Students $30, non-University staff $300 Due to the restricted availability of placements in the course to about 30 people, expressions of interest (EOI) are being sought from interested parties. Your EOI should be sent to Assoc. Prof Silvana Gaudieri at [email protected] by the 11th May 2012 and should include: your name and level of study or position, the name of your research group, affiliation and full contact details plus a brief description (50 words or less) of why this course will be useful to your research. Selected individuals will be notified within a week of the submission date with payment due by the 18th of May 2012. Payment can be made by cheque (payable to the “University of Western Australia”) or by IFT form (addressed to Mr Max Hutchens, M309). Participants are expected to bring their own computer to use during the 3-day course.
Thursday 14
17:00 - PERFORMANCE - School of Music: DMA lecture-recital More Information
DMA candidate Clare Tunney will be giving her final lecture-recital on the Bel Canto Cello next Thursday 14 June (5pm) in the Eileen Joyce Studio.

Entry is free, all welcome!
Wednesday 20
16:00 - SEMINAR - 'To QC or to multi-level QC: A next generation DNA sequencing problem' Website | More Information
Dr Barrero is a Senior Research Fellow at the Centre for Comparative Genomics at Murdoch University. Dr Barrero was awarded a MONBUSHO (Ministry of Education, Culture, Sports, Science, and Technology, Government of Japan) Scholarship to conduct his Master (1996-1998) and Doctoral (1998-2002) studies at the Graduate School of Biological Sciences at the University of Tokyo, Japan. In 2002 he joined the “Japan Biological Information Research Center” in Tokyo as a postdoctoral fellow where he was involved in large collaborative international project aiming to functionally annotate all human genes. He coordinated the discoveries of alternative splicing isoforms and novel non-coding RNAs in the human transcriptome. In 2004 he was recruited to join the National Institute of Genetics, one of the oldest research institutes in Japan, as an Assistant Professor. There he contributed to another large international collaborative project aiming to characterize the rice transcriptome. In 2005 as part of a collaboration with Prof. Bellgard, he visited Perth and fell in love with the city. Late 2006 he joined the Centre for Comparative Genomics at Murdoch University where he has been involved in leading various bioinformatics projects within the NCRIS 5.1 (National Collaborative Research Infrastructure) initiative. Along with his NCRIS 5.1 duties Dr Barrero has been engaged in various research collaborations with local, national and international collaborators in the area of genomics and transcriptomics including microRNAs.
Friday 22
10:00 - EVENT - UWA Careers Centre - Wageline Interviews : Department of Commerce, Labour Relations is conducting interviews on campus. Website | More Information
Labour Relations Officer role:

Provides information to private sector clients on State awards, agreements and industrial legislation through the Wageline call centre.

Contributes to the services provided by Wageline to promote compliance with State employment laws.

See also Labour Relations Officer job on CareerHub.

To apply, come to the interview session: Informal interviews are being held on Friday 22 June 2012 between 10.00am and 3.00pm at the Careers Centre, 1st Floor Reception, Student Services Building, University of Western Australia, Nedlands. Simply bring along your resume and fill in an application form on the day. Allow 10 minutes for the informal interview.

There will be a second assessment if successful.
Wednesday 27
16:00 - SEMINAR - “Signalling pathways intersected by the Src family tyrosine kinase Lyn involved in blood development and cancer” Website | More Information
Associate Professor Evan Ingley heads the Cell Signalling group at WAIMR, which has an interest in understanding the signalling networks or "information highways" of both normal and diseased cells. Many of the new generation anti-cancer drugs disrupt these signalling networks and bring about a "normalization" of protein interactions/pathways. One of the underlying control mechanisms of these processes is that of regulated protein-protein interactions through post-translational modifications such as phosphorylation. A/Prof Ingley's group focuses on an enzyme, Lyn, which modifies proteins via specific phosphorylation on tyrosine residues and through this process mediates specific protein interactions that can enhance or hinder particular cellular processes including cell growth, shape, movement, differentiation and death. Currently his research group is analysing the biological and signalling consequences of mice expressing mutants of Lyn that either inhibit its activity of enhance its activity; how the Lyn substrate Csk binding protein (Cbp) can be used to disrupt Lyn signals in cancer cells; delineating a novel Lyn signalling pathway mediated by AFAP1L1 that controls cancer cell invasion/metastasis; and the novel molecule Liar, which regulates nuclear/cytoplasmic shuttling.
Saturday 30
14:00 - EXHIBITION - Jimmy Pike Artlines - You Call it Desert, We Used to Live There : Exhibition Focus Day More Information
Following the official opening of Jimmy Pike’s Artlines: You call it desert, we used to live there, the Berndt Museum will be hosting an exhibition focus day. This will provide members of the public the opportunity to witness spectacular music and dance performances as well as to hear from the family of Jimmy Pike and the curators of the exhibition to gain an in depth understanding of the artworks and their creator.

Afternoon tea will be served.

Please RSVP by Friday 29 June to Alexandra Tough on [email protected] or (08) 6488 3079

 July 2012
Thursday 05
18:00 - SCREENING - The Quest of Jimmy Pike (1990, 51 Minutes, G) : Free Film Screening More Information
The Quest of Jimmy Pike demonstrates the extraordinary life of internationally renowned artist Jimmy Pike, a Walmajarri man who became an artist through the most unlikely of circumstances. The film depicts Jimmy Pike’s introduction to art and the story behind the man that became an Australian icon.

The Lawrence Wilson Art Gallery will be open in the evening from 5-6pm for a special viewing of the exhibition prior to the film.

Limited seating, please RSVP by Friday 29 June to Alexandra Tough on [email protected] or (08) 6488 3079
Wednesday 11
16:00 - SEMINAR - “Establishing stem cell lines from mammary and lung tissue – plating at the University of Melbourne and waiting at Melbourne Park” Website | More Information
George Yeoh has a long standing interest in liver stem cells, specifically liver progenitor cells (LPCs) which are bipotential and able to generate hepatocytes and cholangiocytes in vitro and in vivo. His lab has gained valuable insight into the biology of LPCs by studying cell lines that are derived from liver using the “plate and wait” method he acquired while on sabbatical at the Pasteur Institute in Paris. In this seminar, an update on new findings on LPCs will be presented.

During the Austraian Open Tennis season, George applied the plate and wait method on cells isolated from the mammary gland by the Lisse-Labat/Visvader group at the WEHI and from the lung by the McQualter/Bertoncello group in Pharmacology at the University of Melbourne. These experiments and progress with establishing a mammary progenitor cell line and a lung progenitor cell line respectively will be discussed. Images and video from the Australian Open will also be presented.
Friday 13
19:30 - PERFORMANCE - School of Music Presents: Brass Feast More Information
In collaboration with The University Club of Western Australia, The School of Music proudly presents Brass Royalty and World Artists Robert and David Childs. Joined on stage by Perth’s own Royal Agricultural Society Brass Band of WA, these world-renowned Euphonium players are both in high demand across the world.

Robert Childs is a leading figure in the world of brass music. For over thirty years he has performed at the highest level giving solo performances in many of the world’s most prestigious venues. He is now the Musical Director of The Cory Band.

David Childs has emerged as one of the finest brass soloists in the world today. Since winning the brass final of the BBC Young Musician of the Year in 2000, he has not ceased to wow audiences with his astonishing technique, extrovert musicality and engaging stage presence.

Don’t miss this once in a lifetime opportunity to see father and son together in performance.

For bookings please contact the University Club of Western Australia: Telephone 6488 8770 (Monday - Friday 9.00am - 8.00pm)

Price (includes canapé reception) Standard $65 Friends of UWA School of Music $60 The University Club of Western Australia Member $60
Wednesday 18
16:00 - SEMINAR - “Allo-HLA reactivity by virus-specific memory T cells” Website | More Information
Dr Lloyd D’Orsogna is a Clinical Immunologist and fellow of both the Royal Australian College of Physicians (RACP) and Royal College of Pathologists of Australiasia (RCPA). He is a new investigator recently returned from overseas after completing his PhD studies with honours (Cum Laude) in the field of transplantation biology and immunogenetics, at the Leiden University Medical Centre, the Netherlands. His research focuses on crossreactivity of virus specific memory T-cells against allogeneic HLA molecules and has led to novel understanding of the nature of T-cell alloreactivity. He has published many papers including a key paper on the high frequency and nature of allo-HLA crossreactivity by viral specific memory T-cells published in the journal Blood (Blood 2010; 115: 3146-3157). His research has been awarded multiple prizes including the prestigious Julia Bodmer Award 2011 (Young investigator award) by the European Federation for Immunogenetics (EFI).

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