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Today's date is Friday, July 10, 2020
School of Molecular Sciences
 April 2012
Wednesday 11
9:00 - COURSE - Introduction to Statistics using MS Excel : A Short Course Website | More Information
The aim of this course is to give the participants an introduction to the facilities available in MS Excel from a statistical point of view. As well as an introduction to Excel, spreadsheet functions and graphics, we concentrate on performing basic statistical methods, producing charts and tables, and discuss the limitations of Excel when it comes to more complex statistical analysis.
Friday 13
9:00 - COURSE - Semiparametric Regression : A Short Course Website | More Information
Semiparametric regression is concerned with the exible incorporation of nonlinear functional relationships in regression analyses. Assuming only a basic familiarity with ordinary regression, this short-course explains the techniques and bene ts of semiparametric regression in a concise and modular fashion. Spline functions, linear mixed models and Bayesian hierarchical models are shown to play an important role in semiparametric regression. There will be a strong emphasis on implementation in R and BUGS.

Registration for the course is available online at https://scg.maths.uwa.edu.au/?id=347

16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Abbie Creamer and Dr Jacky Bentel : Seminar presentation : Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have 2 presenters, Abbie Creamer (Honours Student) from Murdoch University present her proposal presentation on 'ETS1 Modification of the Hormone Responsiveness of Breast Cancer' and Dr Jacky Bentel from Anatomical Pathology (Royal Perth Hospital) present on 'Harry Potter and the 2012 AACR Advances in Prostate Cancer Research Conference'. Series are sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Wednesday 18
13:20 - Forum - Bioenergy Forum : The Energy and Minerals Institute along with the School of Chemistry and Biochemistry are pleased to invite you to The University of Western Australia’s Bioenergy Forum Website | More Information


Microalgae Energy Farms for Low Cost Biodiesel Production Presented by Dr Peer Schenk

ABSTRACT: From start to finish, biodiesel production from microalgae requires optimisation of all steps towards cost effectiveness and energy efficiency, as current limitations exist mainly in the industrial feasibility of microalgae systems. Our team is developing improved non-GM Australian microalgae strains, as well as low cost algae cultivation and harvesting systems to provide a cost & energy effective biodiesel production module. This module utilises microalgae's potential as zero-waste biorefineries, producing not only bioenergy, but also protein-rich animal feedstock and high-value products such as Omega-3 fatty acids. Our research group maintains a growing collection of marine and freshwater microalgae from Queensland, whereby high lipid yielding strains are screened and selected for improvement. We use adaptive evolution methods incorporating mutagenesis and high throughput selection for high-lipid yielding strains. These are then used in especially engineered "Split-System" cultivation units that incorporate both, a low cost photobioreactor (PBR) coupled with several extensive raceway ponds. In the PBR, optimal culture conditions are maintained with daily culture harvested into the raceway ponds to stimulate lipid biosynthesis. Several harvesting and lipid extraction.

Autotrophic Production of Algal Biofuel: What is the best technology line-up Presented by Dr Skye Thomas-Hall

ABSTRACT: Microalgae have the potential to produce 10-20 times more biofuel feedstock per unit area than any terrestrial bioenergy crop. However for this to be economically viable, three important technology stages need to come together: i) cultivation of high lipid species must be relatively contamination free and highly productive (ideally AFDW in excess of 30 g m-2 d-1); ii) the biomass needs to be harvested quickly using energy efficient technology; and iii) the harvested algae should be processed into stable products before value is lost. Cellana LLC was formed in 2008 with the primary aim of developing the technology pathway to make algal biofuels economically viable. Cellana’s 2.5ha Kona Demonstration Facility (KDF) is located on the Big Island of Hawaii and has been producing high quality algal biomass since 2009. The production can be tailored to customer needs for different fractions of the algal biomass, including lipids for biodiesel, protein for animal feed, essential fatty acids (i.e. EPA, DHA) and accessory pigments (e.g. lutein, ß-carotene, lycopene etc) for the nutrition and cosmetic industries. Cellana’s KDF is primarily a research facility, designed to test many algal species simultaneously (up to 12) in realistic outdoor conditions. The large scale hybrid system can grow 2 species simultaneously and has excellent flexibility that enables cultivation conditions to be optimized for each individual strain. The facility is also set up to test a variety of harvesting and dewatering techniques on each species grown at demonstrations scale (up to 780,000 L). Presented is an overview of strain selection at small scale (lab <1 L) and mid scale (outdoor 200 L). Growth parameters that can be altered for optimizing cultivation at mid scale and large scale (60,000 – 130,000 L). The majority of the presentation is on harvesting and processing techniques used by Cellana and in the wider algae industry, focusing on cost versus efficiency of methods trialed at Cellana’s Kona Demonstration Facility (KDF). Best handling and storage practices are also presented along with data analysis specifically focusing on lipid quality.
Thursday 19
16:00 - VISITING SPEAKER - A universal code for RNA-protein recognition : PLEASE NOTE TIME CHANGE !!! Previously 1pm, now 4pm. More Information
RNA-protein complexes play essential roles in the regulation of gene expression, by orchestrating the basic growth and maintenance of the cell as well as the complex developmental programs of multicellular eukaryotes. The modes by which proteins bind RNA are diverse and often difficult to predict, limiting our ability to engineer RNA-binding proteins for practical applications. Engineering RNA-binding proteins is attractive because they could be fused to any desired effector domain, enabling selective binding of a specific RNA target to investigate or manipulate any aspect of its metabolism. We have used directed evolution to expand the recognition of Pumilio and FBF homology (PUF) repeats beyond adenine, guanine and uracil and evolved them to specifically bind cytosine. These repeat sequences can be used to create PUF domains capable of binding RNA targets of diverse sequence and structure enabling many potential biological and medical applications.
Friday 20
16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Associate Professor Steven Mutsaers: Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have Associate Professor Steven Mutsaers a local speaker from the Lung Institute of Western Australia, present on "Regulation of lung fibrosis through STAT3-mediated pathways". Event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Thursday 26
16:00 - VISITING SPEAKER - High affinity phosphate transporters in Arabidopsis: a complex story! : PHT1 high affinity Pi transporters belong to a highly multigenic family of genes. More Information
The PHT1 high affinity Pi transporters belong to a highly multigenic family of genes. They are tightly regulated spatially and temporally by Pi supply at transcriptional and post-translational level. Combinations of genetic, cell biology and molecular biology experiment will be presented to dissect elements of this complexity.
Friday 27
16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Doctor Miriam Calao: Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a national speaker visiting from Sydney, NSW. Dr Miriam Calao from the Virology Lab, Abbot Laboratories, presenting on "Strategies for Purging the Latent HIV-1 Reservoirs: Can HIV-1 infection be eradicated?" Event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Monday 30
12:00 - VISITING SPEAKER - LIWA Medical Research Seminar Series : Prof Jose Porcel presents "Pleural Fluid Biomarkers" Website | More Information
LIWA invites you to a free seminar on: "Pleural Fluid Biomarkers" by Professor Jose Porcel from Department of Internal Medicine, Arnau de Vilanova University Hospital, Spain. Time: 12 noon for light lunch with 12.30pm – 1.30pm presentation.

 May 2012
Tuesday 01
13:00 - TALK - UWA Careers Centre - Water Corporation Employer Talk : Water Corporation graduate recruitment presentation Website | More Information
Water Corporation representatives will be on campus to talk about graduate opportunities for all students. (engineering and science highly desired) Please book through https://uwa.careerhub.com.au
Wednesday 02
12:00 - SEMINAR - Soil&Water Seminar, May2: : "Application of next-generation DNA sequencing to the analysis of long and short PCR products " More Information
The Soil&Water seminar at 12pm on Weds, May 2nd, will be given by Richard Allcock, with an introduction by Tony O'Donnell, Dean of Science. All welcome!

TITLE: "Application of next-generation DNA sequencing to the analysis of long and short PCR products"

Richard Allcock is the Scientist-in-Charge of the LotteryWest State Biomedical Facility – Genomics (LSBFG) based at Royal Perth Hospital. He is also a member of the School of Pathology and Laboratory Medicine at the University of Western Australia and a Founding Fellow of the Faculty of Science of the Royal College of Pathologists of Australasia. He has expertise in the analysis of DNA and detection of sequence variants. Under his direction, LSBFG performs next-generation sequencing (FLX/454, SOLID, Ion Torrent) Sanger sequencing and a host of other genetic and genomic analyses. Richard Allcock has analysed many DNA sequence variants and their affect on function, haplotypic arrangements and role in disease susceptibility/resistance. He has published widely in this area, collaborating with many researchers across Western Australia and internationally.

As a sequencing tragic, Richard has established links with Tony O’Donnell and Andrew Whiteley to see how these sequencing technologies can be routinely and cheaply applied to the analysis of agricultural and environmental samples. As part of this collaboration FNAS have funded an ion Torrent PGM sequencer housed at Royal Perth Hospital and it is this device that he’ll be talking about today.

13:00 - SEMINAR - Muscle Mechanics and Energetics in Locomotion: From Basic Research to Human Health : School of Anatomy, Physiology & Human Biology Seminar Series Website | More Information
The Seminar: Dr Rubenson will discuss his work aimed at understanding the relationships between in vivo muscle function, locomotor mechanics and it associated metabolic energy cost. Dr Rubenson will discuss projects adopting experimental and modeling approaches in both humans and animal systems. His projects span basic research questions requiring direct muscle mechanics and energetics measurements (e.g. muscle strain, force, muscle blood flow) as well as clinical research questions, in particular into muscle mechanics and energetics in ageing and chronic heart failure.

The Speaker: Dr Jonas Rubenson is an Assistant Professor in the Biomechanics Group within the School of Sport Science, Exercise & Health at UWA. His expertise lies in study of musculoskeletal mechanics, in particular in vivo muscle function during movement and the relationship between muscle function and locomotor energetics. Dr Rubenson received his PhD from the University of Western Australia, where he studied the role of mechanical energetics as a determinant of the energy cost of bipedal running. Subsequent post-doctoral positions at Northeastern University (Boston, MA) and Stanford University (Stanford, CA) saw Dr Rubenson gain expertise in both mechanical and energetic measurements of skeletal muscle in animal models (e.g. sonomicrometery and blood flow measurements) as well as experimental measurement and musculoskeletal modelling of muscle function in humans.
Friday 04
16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Associate Professor Fiona Pixley: Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a local speaker. Associate Professor Fiona Pixley from the School of Medicine and Pharmacology, University of Western Australia, presenting on "Targeting CSF-1 induced macrophage migration to inhibit tumour invasion and metastasis" Event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Tuesday 15
13:00 - SEMINAR - Nucleic acid sequencing technologies: Wows and Woes : School of Anatomy, Physiology & Human Biology Seminar Series More Information
The Speaker: Dr Watson trained as a molecular biologist in the United Kingdom and conducted his first post doc with Prof Steven Holgate, Prof Newton Morten and Prof. Patricia Jacobs in Southampton , UK performing genetic linkage analysis to Atopy and allergic disease. In 1994 he took up a position as the manager of the Centre for Cell and molecular Biology at the University of Western Australia.

In 1996 he was successful in obtaining NH&MRC funding for a project looking at the molecular aspects of the Murine AIDS virus. Dr Watson then moved to a research position within the WA Health Department at Royal Perth Hospital Department of Microbiology and Infectious Diseases to study the Hepatitis C Virus which remains one of his main research areas to date.

In 2006 Dr Watson took up the position of Manager of the newly established Geomics Node of the Lotterywset Biomedical facility located within the Department of Immunology and Immunogenetics at Royal Perth Hospital.

Dr Watson has been highly active in organising conferences both local and national (CBSM and ASM) and has previously chaired CBSM 92002-2005). Dr Watson is an ASMWA committee member and is the chair of the WA health Hepatitis C Virus statewide database development group.

He joined the Institute for Immunology and Infectious Diseases as the Laboratory Manager in December 2008. His most active area of current research is in the area of the Hepatitis C virus with particular focus on molecular immunology and antivirals.

13:00 - Demonstration / Open Day - Demonstration / Open Day : CMCA: Hawker Richardson Products for Productivity More Information
- Obligation free hands on demonstrations - Bring and try your own samples - Patented eye-pieceless optics allows operators freedomn of head movement with the ability to wear glasses - Superb Ergonomics reduces eye strain and fatigue - Pin sharp iomage with long working distances - Bright LED illumination ideal for all Inspection applications and manipulation tasks

Lynx - Stereo Dynascopic Microscope for inspection and material rework

- Wide range of magnification x3.5 - x120 - Patented stereo eyepieceless optical technology provides superb resolution and contrast - Easy hand-to-eye coordination resulting in increased throughput, accuracy and reduced scrap - Long-life, true colour LED illumination for shadow-free viewing of complex surfaces

Mantis - Stereo Viewing Systems Superior imaging for a wide range of inspection & rework tasks

- Patented optical technology for fatigue-free viewing and superb image quality - Wide range of magnification options (to x20) - Long working distances; large depths of field - Shadow-free true colour LED illumination
Thursday 17
16:00 - VISITING SPEAKER - Post-transcriptional chloroplast gene regulation: Analysis of key ribonucleases responsible for RNA maturation : Regulation of chloroplast gene expression has levels of complexity not found in prokaryotes. More Information
Dr Sharwood’s research focuses on the molecular engineering of higher plant chloroplasts to improve many facets of plant productivity. Chloroplasts harbour the key biochemical reactions of photosynthesis, a process that underpins all life on earth.
Friday 18
16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Doctor Brian Brestovac: Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a local speaker. Doctor Brian Brestovac from the School of Biomedical Sciences, Curtin University presenting on "Human papillomavirus (HPV), Cervical Intraepithelial Neoplasia (CIN) and Killer Immunoglobulin-like Receptors (KIR)". The event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Tuesday 22
13:00 - SEMINAR - Integrating the fields of neuroscience and ecology to understand animal behaviour : School of Anatomy, Physiology & Human Biology Seminar Series More Information
The Seminar: By investigating the neural basis of behaviour in marine organisms, it is possible to identify the signals that govern a range of behaviours crucial for survival. In this presentation, the fields of neuroscience and ecology are integrated to explore animal behaviour and the processing of environmental signals by both the peripheral and central nervous systems of a range of (predominantly marine) organisms. Within every species’ microhabitat, the ability to detect the physical environment for setting circadian rhythms, avoiding predation, finding food and for reproductive success are often different. We use innovative neurobiological techniques such as molecular genetics, microspectrophotometry, bioimaging, electrophysiology and anatomy to trace the evolution of sensory systems and the detection thresholds for light, chemosensory signals, electric fields, water borne sound and hydrodynamic disturbances. In this way, we hope to understand how we can protect biodiversity and the varied environments each species is adapted to.

The Speaker: Professor Shaun P. Collin is a WA Premiers Research Fellow and Winthrop Professor at The University of Western Australia. He heads a large Neuroecology Group that investigates the neural basis of behaviour in both invertebrates and vertebrates, with special emphasis on sensory systems and vision. Before joining UWA from The University of Queensland, where he was a Professor within the School of Biomedical Sciences for 10 years, he spent appreciable periods of time in Canada, the United States, Germany and Australia on a range of prestigious Research Fellowships (ARC QEII, Fulbright, Alexander von Humboldt, Grass). Using a range of cutting edge techniques, his Group investigates the impacts of light on biodiversity, sustainability and health in a large diversity of animals, including humans. Prof. Collin has published over 170 scientific papers, including 2 books, and sits on the Editorial Boards of 5 international journals. He also sits on the College of Experts Panel for the Australian Research Council (ARC) and is a member of the Technology and Innovation Advisory Council (TIAC) for the WA State Government.
Friday 25
16:00 - SEMINAR - PaLM Seminar Series (RPH) 2012 - Abdullah Ali Aseeri and Royston Ong: Seminar presentation More Information
All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are delighted to have 2 of our own students presenting final MLM and honours seminars respectively: Abdullah Ali Aseeri on 'Identification and discrimination of different strains of CA-MRSA by using MALDI-TOF MS' and Royston Ong on 'Whole exome sequencing applied to Charcot-Marie-Tooth (CMT) Disease' from the School of Pathology and Laboratory Medicine, UWA. The event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!
Monday 28
12:00 - SEMINAR - LIWA Medical Research Seminar Series : By Prof Graham Hall, "Lung function – going global in 2012" Website | More Information
The Lung Institute of WA invites you to a free seminar on: "Lung function – going global in 2012" by Professor Graham Hall from the Telethon Institute for Child Health Research. Time: 12 noon for light lunch with 12.30pm – 1.30pm presentation.

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