What's On at UWA

Prof Bill Cookson of Imperial College London discusses "Asthma: genes versus the microbiome at the airway barrier". A light lunch follows the presentation.

William Cookson is Professor of Genomic Medicine at Imperial College London and Head of Respiratory Sciences for the College. He is Head of the Asmarley Centre for Genomic Medicine at the National Heart and Lung Institute. He won a Joint Wellcome Senior Investigator Award with Professor Miriam (...)

The framework structures of nanoporous crystals are varied and complex and the solutions from which the crystals grow a soup of hundreds of pre-nucleation species each competing for supremacy. Yet conditions can normally be found under which it is possible to prepare a pure phase where there is one (...)

The cassava plant which millions of families in East Africa depend on for there daily calories is under attack by the African cassava whitefly, Bemisia tabaci which is a small sap sucking insect causing extensive damage to major food staples in all parts of the world. B. tabaci is a species (...)

I will describe the natural, stepwise evolutionary journey that lead to the creation of a novel, functional peptide in sunflower seeds. This peptide, Sunflower Trypsin Inhibitor‑1 (SFTI‑1) originates within the same coding sequence as a seed storage albumin called PawS1 and is (...)

The self-assembly of multi-nuclear metallosupramolecular architectures has received significant recent attention due to potential applications in host-guest chemistry and catalysis. The programmed formation of these beautiful and complex systems generally results from the combination of the (...)

The MSGPP collaboration has used structural genomics, targeted genetics, and synthetic chemistry to identify, validate, and exploit potential drug targets in parasitic protozoa. One notable success from this approach has targeted Calcium-Dependent Protein Kinases (CDPKs), a class of proteins found (...)

DNA methylation (5mC) is a gene regulatory mechanism that is associated with repressed transcription through recruitment of methyl binding proteins or by physically blocking transcription factor binding. DNA methylation typically occurs in the CpG dinucleotide context where a methyl group is added (...)

Biological function in organisms and cells is maintained by signalling pathways of inter-related proteins responding to internal and external stimuli. The activities of many of the proteins involved in cell signalling are susceptible to redox changes caused by reversible oxidation of protein thiol (...)

My research interests over the last 4 years have been in three distinct and different areas. In this talk I will highlight the recent progress made in all three areas.

S1. Chemical properties of the (001) β-Ga2O3 surface Monoclinic β-Ga2O3 is an n-type semiconductor (...)

Previous work in our lab, using fluorescent adenosine receptor agonists and antagonists, has provided novel insights into the allosteric regulation of adenosine A3 (A3AR) and A1 (A1AR) receptors by allosteric ligands and receptor dimerization in single living cells (1-2). We have also used a (...)

Professor Stephen Hill studied Pharmacology in Bristol (BSc, 1976) and then undertook PhD studies in the Department of Pharmacology in Cambridge (PhD 1979). After postdoctoral studies in Cambridge (1979-1981) he was appointed to a lecturer position in the Department of Pharmacy at the University of (...)

Twin-arginine translocation pathways have been identified in all domains of life. However in the eukaryotic domain they were thought to be only found in chloroplasts even though almost all plant mitochondrial genomes encode for a TatC protein. Our recent work has demonstrated that in Arabidopsis (...)

In the absence of large, randomised, well-controlled clinical trials (with independent replication) to address every research question we all need to increase our statistical literacy. We are often faced with the need to critically assess grant applications, manuscripts or reports without a (...)

The Gold Standard GAMSAT will host a GAMSAT Practice Test & Review seminar on Feb 4 - 5, 2016 at University Hall, University of Western Australia. The course will start at 9 am and ends at 6 pm daily.

The tutor of this course is Dr. Brett Ferdinand, author of the Gold Standard (...)