What's On at UWA

The primary transcripts must then undergo extensive processing, including the maturation of 5’ and 3’ termini, RNA-editing and the splicing of many group-II-type introns (the precise number varying by species), which lie mainly within complex I subunits but also disrupt the coding-regions of several genes encoding ribosomal proteins. The splicing of these introns is therefore essential for the expression of the coding sequences they interrupt, and thus for respiratory activity. Yet, despite the importance of proteins that influence mitochondrial gene-expression, functions have been established for only a handful of such proteins in plants. In non-plant systems, the splicing of group-II introns is facilitated by proteins encoded within the introns themselves (Maturases, Mat’s). Yet, the plant mitochondrial introns are degenerated and also lost their intron-encoded ORF. It is thus anticipated that their splicing in the organelles requires the participation of nuclear gene products. In addition, the roles of nuclear-encoded factors in mitochondrial RNA-metabolism may provide means to link organellar gene expression and function to other cellular responses to energy state, environmental stimuli, and/or developmental cues. However, the precise functions still remain largely unknown for many of these proteins in plant mitochondria. By using biochemical and genetic approaches we established the roles of different proteins in the splicing of many of the mitochondrial introns in plants. These are diverse in origin and presumably in mechanism. Defects in interactions between this class of proteins and their RNA partners have been linked to growth and developmental defects, which include reduced germination, retarded growth phenotypes and cytoplasmic male sterility.

The course is designed for people with little or no knowledge of statistics. It will be spread over three days covering material ranging from means and standard deviations to simple linear regression, and basic ANOVA. Some basic categorical data analysis will be included with the emphasis throughout being placed on applications rather than theory. The statistical package SPSS will be used to illustrate ideas demonstrated, however this course is aimed at enabling an understanding of basic statistics.

Come and hear prominent UWA, national and international speakers give varied and fascinating insights into Innovative Discoveries in Science through Advanced Mass Spectrometry. A full list of speakers and seminar titles is available on request to [email protected]

You are invited to attend this live demonstration of the new Hirox KH-8700. This will be an overview of the system and demonstration including the 3D rotary lenses, multifocal functions and a variety of unique lenses and adaptors. All are welcome to attend.

All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a local speaker. Doctor Keith Giles from the Laboratory for Cancer Medicine, Western Australian Institute for Medical Research presenting on "Regulation of epidermal growth factor receptor signalling in cancer by microRNA-7". The event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!

We hypothesize that the massive changes in C4/C3 related gene expression are controlled by a subset of transcriptional regulators, which are essential for C4 photosynthesis establishment and/or maintenance. We analyze the Cleome genus, which includes closely related C4 (Cleome gynandra) and C3 (Cleome hassleriana) species and exhibits phylogenetic proximity to the model species Arabidopsis thaliana.In order to elucidate the regulatory network behind the C4 syndrome in Cleome we are employing two strategies: (i) A single candidate gene approach derived from a global comparative analysis of transcriptome data sets of C4/C3 species (including Cleome hassleriana and gynandra) generated by 454 and Solexa sequencing, which targets will be further described biochemically and genetically (e.g. via over-expressor and knock-out lines in Arabidopsis thaliana) and (ii) co-expression analysis for the identification of the regulatory modules which will include a developmental gradient of photosynthetic and a subset of non-photosynthetic tissues.

"Our research focuses upon how the virulent bacterial phytopathogen Pseudomonas syringae establishes disease in the model plant Arabidopsis thaliana. P. syringae delivers a suite of ~ 30 effector proteins into the plant cell." Detailed abstract available [email protected]

Join us in an afternoon of information and debate about one of agriculture's hottest current topics: Prominent industry leaders will discuss foreign ownership of Australian agricultural land and agri-business, its challenges, opportunities and its potential impacts on farming families and agricultural industries. For program details and speakers click on the link below.

This talk will present the theories and curatorial decisions behind a recent exhibition by Donna Franklin as a part of her PhD research at Edith Cowan University. The exhibition included works of local, national, and international interdisciplinary artists. The artworks selected for the exhibition will be discussed in relation to Franklin’s interest in the communicative role the arts plays: In particular as a site of interrogation into aspects of “systemic colonisation” and the “life world” concerning future cultural engagement with non-human life (Habermas, 1970). Creatures of the Future Garden as an exhibition aimed to engender the development of gallery spaces that facilitate multiple uses: As a site of conservation, wilderness and education (Gessert). Franklin is seeking audience opinion regarding the exhibition and workshop presentations with the intention of generating further interest in animal welfare, the environment, science and arts, in as many diverse contexts as possible. This puts into practice Franklin’s passion for generating real-time experiences with non-human life, and hands-on education, as strategies to explore the natural world and examine biotech futures. Exhibiting Artists: Dr Trish Adams, Tarsh Bates, Donna Franklin, George Gessert, Alexandra Daisy Ginsberg, Kirsten Hudson, Svenja Kratz, Angela Singer, The Made Generation: Gary & Susie Cass, Jesse Brown, Nicholas Lozanovski, Sasha Whittle.

Franklin is currently a PhD candidate (Philosophy) and academic in Cultural History and Theory at The School of Communication and Contemporary Arts, Edith Cowan University. Her various research projects investigate the role art/science collaboration has in generating public awareness and debate raised by developing biotechnologies or investigates ecology environment. She has a particular interest in creating artworks that explore an engagement with the non-human, such as fungi, plants and animals. During her Master of Arts, she was awarded an artist residency at SymbioticA: Centre for Excellence in Biological Arts, UWA. She has collaborated with scientists and artists to produce artworks and conduct art/science workshops for festivals, galleries and schools. Selected exhibitions include: Animals People: A shared environment POP Gallery Brisbane 2011, Signs of Change Form Gallery 2010, SuperHuman RMIT Melbourne 2009, Biotech revisited EAF 2008, Skin to Skin FAC08. Techno Threads Science Gallery Dublin 2008, ARS Electronica Festival 07, Mycologia Mundaring Arts Centre 2007, Second Skin ENTRY06 Vitra Design Museum Germany and Taiwan 2007, BEAPworks06 Australia, Hatched 05 PICA, BEAP04.

The course is designed for people with knowledge of basic statistics who want to learn more about regression and analysis of variance (ANOVA).

The course is hosted by the Centre for Applied Statistics and we offer discounted rate fees to UWA Graduate Research Students.

Fee information is available on our website cas.maths.uwa.edu.au. Please register online.

The 3MT competition challenges research students to give a dynamic and engaging presentation about their research and its significance in a way that can be understood by everybody. The audience will select the "People's Choice" winner.

The course is designed for people with knowledge of basic statistics who want to learn more about how to analyse binary or survival data.

The course is hosted by the Centre for Applied Statistics and we offer discounted rate fees to UWA Graduate Research Students.

Fee information is available on our website http://www.cas.maths.uwa.edu.au/courses. Please register online.

All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a local speaker. Professor Charles Watson from the school of Health Sciences, Curtin University presenting on "The genetic map of the hindbrain - why you should avoid using the terms 'pons' and 'medulla'". The event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!

What makes a healthy start to life? This is the single overarching question and focus of the NRCD, a New Zealand government-funded Centre of Research Excellence, bringing together leading scientists from six organisations across New Zealand to answer this question. Acting Director, Prof Hugh Blair, is leading several projects investigating the effects of fetal programming on later life productivity in sheep and cattle and the possibility that these programming effects may be transmitted between generations. His public lecture examines how this applies to sheep, focusing on how a mother's eating habits affect her daughters' milk production.

With the recently acquired IVIS Lumina and Maestro instruments at UWA, researchers now have the ability to longitudinally and non-invasively monitor cancer (and other disease states) in small animal models using optical light. This seminar is intended to provide a high-level overview of the capabilities on the instruments, as well as answer any user specific questions. Focus areas will include: Monitoring tumour growth, Stem Cell research and Atherosclerosis, Tracking gene expression

Paul Sharp is founder of Two Hands Project and works on issues of plastic pollution, particularly in the marine environment. Two Hands Project is a collaborative approach to dealing with plastic pollution: take 30 Minutes and Two Hands to clean up yOUR world anytime, anywhere.

Two Hands embodies the spirit of the huge national/international clean up days but asks what you can do with your two hands in 30 minutes, at a location near you, on any day of the year. We are taking it all back to grass roots, looking at what you can do to care for the place(s) that are near to you or important to you, anytime that you want. Whether you’re doing this to improve the health of our oceans, reduce the risk to wildlife or to simply clean up unsightly trash in one of your favorite parks or beaches, what you can do with your own Two Hands is easy.

Sharp will be talking about his recent experiences in the North Pacific, where he was part of the 5 Gyres/Algalita Marine Research Foundation Tsunami Debris Expedition.

twohandsproject.org

All welcome to attend the School of Pathology & Laboratory Medicine 2012 Seminar Series (RPH). On a weekly basis we have local/guest speakers presenting to a wide audience typically in the fields of immunology, molecular biology and cancer related research. This week we are privileged to have a local speaker. Doctor Zak Hughes from the Nanochemistry Research Institute, Curtin University presenting on "Using Molecular Simulation to Determine the Effect of Cryosolvents on Phospholipid Bilayers". The event is sponsored by Life Technologies and light refreshments are provided. For further inquiries please contact using the provided email. Look forward to seeing you there!

The Seminar: Fetal glucocorticoid exposure is a key mechanism proposed to underlie prenatal "programming" of adult cardiometabolic and neuropsychiatric disorders. Regulation of fetal glucocorticoid exposure is achieved by the placental and fetal glucocorticoid "barrier," which involves glucocorticoid inactivation by 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2). Mice null for 11beta-HSD2 exhibit altered placental development and function, decreased birth weight, delayed neurodevelopment and increased anxiety and depressive-like behaviour as adults. This raises the question as to whether it is placental or fetal brain 11b-HSD2 that underpins programmed outcomes? Preliminary data suggest that fetal brain 11beta-HSD2 impacts specifically on depressive-like behaviours, but that broader anxiety-related and neurodevelopmental effects are likely to relate to indirect effects of 11-HSD2 in the placenta.

The Speaker: Caitlin completed her PhD at UWA under the supervision of Prof Brendan Waddell and Dr Peter Mark, where she focused on developmental programming and the significance of omega-3 intake in attenuating adverse health outcomes. Caitlin moved to Edinburgh in 2006 to take up a postdoctoral position at The Queen's Medical Research Institute. Here she continued her research interest in developmental programming in the lab of Prof Jonathan Seckl and Prof Megan Holmes. Caitlin then returned to Perth in late 2011 to commence an Assistant Professor position at The School of Anatomy , Phsiology and Human Biology at UWA.

UWA opens up the whole campus to the public.

Come and find out about the courses on offer, career options, scholarship opportunities, our valuable research, community programs and facilities.

There's also residential college tours, hands-on activities, live music and entertainment, and plenty of fun activities for the whole family.

Come along to the Working in WA State Government information session. The session is open to students from all years and all disciplines. You will be surprised at the opportunities available in the public service.

Bookings on CareerHub – http://uwa.careerhub.com.au