EVENT: Glaucoma: what’s on the horizon?
The Lions Eye Institute and the UWA Institute of Advanced Studies present the 2019 Ian Constable Lecture - by Professor Keith Martin, Managing Director, Centre for Eye Research Australia.
Glaucoma remains the leading cause of irreversible blindness worldwide. The field of glaucoma is currently experiencing a renaissance, with multiple innovations in drug delivery and surgery expanding the range of options available to those who treat the disease. Personalised medicine is becoming more common in healthcare and it seems inevitable that this approach will be applied to glaucoma as we attempt to target treatments to those most likely to benefit in a world of constrained resources.
In this lecture, Professor Martin will consider some of the likely developments in glaucoma diagnosis and treatment in the near future, from genomics to continuous IOP monitoring to gene and cell therapies. In particular, studies have found gene therapy approaches to be very promising and Professor Martin will discuss a project using AAV2 vectors to deliver BDNF and its receptor, TrkB, to retinal ganglion cells that is moving rapidly towards clinical translation. Finally, the talk will outline the prospects for optic nerve regeneration – a goal that once seemed impossible that is now becoming conceivable.
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