SEMINAR: School of Human Sciences Seminar Series
|School of Human Sciences Seminar Series : Cancer associated fibroblast mediated remodelling of the extracellular matrix as a driver of tumour progression and metastasis
Homeostasis of the extracellular matrix (ECM) is critical for correct organ and tissue function. It plays a critical role in normal tissue homeostasis and pathological disease progression. Both the biochemical and biomechanical properties of the ECM contribute to modulating the behaviour of resident cells and are more than just passive bystanders. In tissue diseases such as cancer, the ECM undergoes significant change. These changes, driven by both tumour and stromal cells, feed into the progression of the disease. As such, changes in the ECM mark significant transition events in disease progression. Understanding how the changing ECM facilitates tumour progression and metastasis is an important step in the development of new therapeutic approaches for the treatment of cancer.
- Locations of venues on the Crawley and Nedlands campuses are
available via the Campus Maps website.
- Download this event as:
Mail this event: