SEMINAR:
  School of Human Sciences Seminar Series
  - Cancer associated fibroblast mediated remodelling of the extracellular matrix as a driver of tumour progression and metastasis
		
Wed, 04 Sep 2019 14:00 - Seminar Room 1.81, School of Human Science, Anatomy Building
		
Dr Thomas Cox, Group Leader of Matrix and Metastasis at the Kinghorn Cancer Centre
Abstract: Homeostasis of the extracellular matrix (ECM) is critical for
correct organ and tissue function. It plays a critical role in normal
tissue homeostasis and pathological disease progression. Both the
biochemical and biomechanical properties of the ECM contribute to
modulating the behaviour of resident cells and are more than just
passive bystanders. In tissue diseases such as cancer, the ECM undergoes
significant change. These changes, driven by both tumour and stromal
cells, feed into the progression of the disease. As such, changes in the
ECM mark significant transition events in disease progression.
Understanding how the changing ECM facilitates tumour progression and
metastasis is an important step in the development of new therapeutic
approaches for the treatment of cancer.
		
URL: https://www.uwa.edu.au/science/schools/school-of-human-sciences
		
For more information:
  Christine Page
  christine.page@uwa.edu.au
  6488 7126

Starts       : Wed, 04 Sep 2019 14:00
Ends         : Wed, 04 Sep 2019 15:00
		
Last Updated : Wed, 28 Aug 2019 09:10