|Seminar : School of Human Sciences Seminar Series - 16 July (Professor Des Richardson)
The iron-regulated metastasis suppressor N-myc downstream-regulated gene 1 (NDRG1) has been shown to inhibit numerous oncogenic signaling pathways in cancer cells. Recent findings have demonstrated that NDRG1 inhibits the ErbB family of receptors, which function as key inducers of carcinogenesis. NDRG1 attenuates ErbB signaling by inhibiting formation of epidermal growth factor receptor (EGFR)/human epidermal growth factor receptor 2 (HER2) and HER2/HER3 heterodimers and by down-regulating EGFR via a mechanism involving its degradation. Understanding the complex interplay between NDRG1, iron, and ErbB signaling is vital for identifying novel, more effective targets for cancer therapy.
Professor Des Richardson
Room 1.81, School of Human Sciences, Anatomy Building, UWA
Mon, 16 Jul 2018 13:00
Mon, 16 Jul 2018 14:00
Christine Page <[email protected]>
Thu, 19 Jul 2018 14:36
- Locations of venues on the Crawley and Nedlands campuses are
available via the Campus Maps website.
- Download this event as:
Mail this event: