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SEMINAR: Seminar

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Today's date is Friday, February 26, 2021
Seminar : School of Human Sciences Seminar Series - 16 July (Professor Des Richardson) Other events...
The iron-regulated metastasis suppressor N-myc downstream-regulated gene 1 (NDRG1) has been shown to inhibit numerous oncogenic signaling pathways in cancer cells. Recent findings have demonstrated that NDRG1 inhibits the ErbB family of receptors, which function as key inducers of carcinogenesis. NDRG1 attenuates ErbB signaling by inhibiting formation of epidermal growth factor receptor (EGFR)/human epidermal growth factor receptor 2 (HER2) and HER2/HER3 heterodimers and by down-regulating EGFR via a mechanism involving its degradation. Understanding the complex interplay between NDRG1, iron, and ErbB signaling is vital for identifying novel, more effective targets for cancer therapy.
Speaker(s) Professor Des Richardson
Location Room 1.81, School of Human Sciences, Anatomy Building, UWA
Contact Christine Page <[email protected]>
Start Mon, 16 Jul 2018 13:00
End Mon, 16 Jul 2018 14:00
Submitted by Christine Page <[email protected]>
Last Updated Thu, 19 Jul 2018 14:36
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