VISITING SPEAKER: AB SEMINAR SERIES

Pluripotent (embryonic) stem cells have long been an elusive target for livestock as they were seen as the exclusive route for effecting precise genome editing. The first generation of cattle and reprogrammed sheep induced Pluripotent Stem Cells from our lab raised exciting possibilities to realise precise transgenic and genome editing in livestock. Meanwhile, advances in precise and efficient genome editing in mammalian cells and especially zygotes has made the generation of unique animals a reality. In the talk I will present our research using a combination of pluripotent stem cells and advanced genome editing aimed at achieving biomedical and agricultural outcomes.