|Raine Lecture : "How ethnicity matters for medical genomics"
In the past decade, the first human reference genome was generated. Within the last several months, a steep decline in sequencing costs has enabled the analysis of entire populations. However, initial efforts almost entirely concentrated on the sequencing of individuals of European descent and their illnesses, resulting in highly biased SNV (single nucleotide variant) databases. Despite these limitations, large population sequencing projects are underway in the US, UK and Asia, attempting to link rare genetic variants to disease phenotypes. As the major ethnic groups of the human population show noticeable differences in their genetic diversity, this presentation will address issues of genome-based disease associations within study cohorts. In addition, the effect of recent exponential population growth on the generation of novel alleles is investigated, as well as the historical human census sizes of the last 200.000 years.
After receiving a degree in organic chemistry, Stephan Schuster moved into Biochemistry and Microbiology during his graduate studies at the Max-Planck-Institute, Germany. His postdoctoral studies at the California Institute of Technology, Pasadena, USA, included work on bacterial motility and signal transduction. After holding group leader positions at two Max-Planck-Institutes, he was appointed a Professorship for Molecular Microbial Ecology at Pennsylvania State University (Penn State), USA. In 2013, he moved to Nanyang Technological University (NTU), Singapore, as a Professor in Environmental Genomics, and a Research Director at the Singapore Centre on Environmental Life Sciences Engineering (SCELSE). Being one of the pioneers in next-generation sequencing, Professor Schuster has worked on the forefront of technology development and its implementation for research. His works of note include the sequencing of the woolly mammoth, the Tasmanian Tiger and Devil, as well as 2 of the first 10 human genomes
Professor Stephan C Schuster
McCusker Auditorium, Harry Perkins Institute of Medical Research
: 9346 4815
Thu, 25 Sep 2014 12:00
Thu, 25 Sep 2014 13:00
Lyn Ellis <[email protected] >
Fri, 19 Sep 2014 09:02
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