Colloquium: Neurobiology of attention in ADHD: genes, pharmacology and physiology
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Neurobiology of attention in ADHD: genes, pharmacology and physiology |
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Mark Bellgrove is Professor in Cognitive Neuroscience and Larkin’s Fellow in the School of Psychological Sciences at Monash University. Mark’s laboratory studies the neurobiology of attention and cognitive control in both health and disorder (e.g., ADHD) using a range of techniques including molecular genetics, pharmacology, EEG and functional MRI. He is currently funded by an ARC Future Fellowship and his research programmes are supported by the NHMRC.
Attention deficit hyperactivity disorder (ADHD) is a prevalent disorder of childhood with negative adult outcomes. Although subjective ratings of attention deficit are diagnostic for the disorder, delineating an objective attentional phenotype has proven difficult. In this seminar I will present behavioural and electrophysiological data from our laboratory showing that childhood ADHD is associated with anomalous spatial attention akin to a developmental form of the “neglect syndrome”; that this phenotype is ameliorated by treatment with the psychostimulant methylphenidate; and that it can be predicted by common DNA variation in the dopamine transporter gene (DAT1), the gene encoding the molecular target for methylphenidate. These lines of evidence suggest disruption to the hemispheric control of spatial attention in ADHD that is at least partly influenced by dopamine.
Speaker(s) |
Mark A. Bellgrove, PhD
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Location |
The University of Western Australia, Simmonds Lecture Theatre, G01, General Purpose Building 3
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Contact |
David Badcock
<[email protected]>
: 64883267
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Start |
Tue, 23 Sep 2014 13:00
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End |
Tue, 23 Sep 2014 14:00
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Submitted by |
Admin Psy <[email protected]>
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Last Updated |
Tue, 10 Feb 2015 16:23
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