SEMINAR: Ticking off developmental checkpoints: the importance of circadian rhythms during pregnancy
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Ticking off developmental checkpoints: the importance of circadian rhythms during pregnancy : School of Anatomy, Physiology & Human Biology Seminar Series |
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The Speaker: Peter Mark completed a PhD in the Department of Pharmacology at The University of Western Australia in breast cancer research. He investigated the component structure of the estrogen receptor complex in the absence of hormone and determined how this altered the receptor’s response to estrogen. He is currently an Assistant Professor in the School of Anatomy, Physiology & Human Biology at UWA, where he is actively involved in teaching and research in reproductive biology. He is particularly interested in placental factors that act as drivers of fetal growth and development.
The Seminar: Insults during pregnancy, including maternal under/overnutrition, excess fetal glucocorticoid exposure and altered circadian rhythms can result in small for gestational age babies through placental dysfunction. These insults drive physiological and anatomical adaptations in the placenta and fetus, to allow for immediate survival, but predispose the offspring to adult-onset diseases such as hypertension, diabetes and obesity. Our recent research has focussed on circadian rhythms in placental function and how these may impact on nutrient transfer to the developing fetus. Disturbances in maternal circadian rhythms can alter fetal growth trajectories and program offspring for adverse health outcomes, but whether disruption of placental rhythms contributes to these effects is unknown. The presentation will provide evidence for placental circadian rhythms and discuss potential circadian treatments to improve neonatal outcomes for premature babies.
Speaker(s) |
Asst Prof Peter Mark, School of Anatomy, Physiology & Human Biology, UWA
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Location |
Seminar Room 1.81, Anatomy Building north
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Contact |
Debbie Hull
<[email protected]>
: 6488 3313
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Start |
Tue, 13 May 2014 13:00
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End |
Tue, 13 May 2014 14:00
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Submitted by |
Debbie Hull <[email protected]>
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Last Updated |
Tue, 10 Feb 2015 15:38
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