SEMINAR: Intensive Care Research Unit – Opportunities for Perinatal Research Collaboration and Training
|Intensive Care Research Unit – Opportunities for Perinatal Research Collaboration and Training : School of Anatomy, Physiology & Human Biology Seminar Series
The Speaker: Professor Jane Pillow is a clinical academic neonatologist at the University of Western Australia. She is acknowledged internationally as an expert in the area of neonatal respiratory physiology and mechanical ventilation. She has a particular research interest in high-frequency ventilation, having completed her PhD thesis in 2000 on “Optimising High-Frequency Oscillatory Ventilation in Neonates”. Since completing her PhD with Distinction at ICHR, Prof Pillow’s research interests have expanded to focus on ways to minimise lung injury at the initiation of life and include high-frequency jet ventilation, variable ventilation, bubble CPAP, patient triggered ventilation and minimising lung injury during resuscitation. She has obtained over $11 million AUD in research funding, including grants from the NHMRC and the NIH, and is CIA on an NHMRC Centre of Research Excellence. Her preclinical research uses the preterm lamb as a model of neonatal respiratory distress syndrome. She also runs a neonatal lung function laboratory, and is involved in follow-up functional studies of children born prematurely. In addition to her academic responsibilities, Prof Pillow is a Consultant Neonatologist at King Edward Memorial Hospital, where she contributes to the around the clock care of up to 100 babies, including up to 40 infants receiving mechanical ventilator support. Professor Pillow bases her academic activity at the UWA School of Anatomy, Physiology and Human Biology.
The Seminar: Preclinical basic science is challenged increasingly by funding bodies focused on translational research outcomes. Nonetheless, there is little question that the preclinical sciences are a fundamental component of new advances in health care. Animal models of disease offer valuable insights into disease mechanisms, and offer value also for preclinical screening of new and controversial treatment. Preterm infants are a highly vulnerable population, for whom long-term outcomes of clinical interventions have life-long implications. A clinically relevant postnatal animal model offers rapid evaluation of safety, efficacy and long-term outcomes of new and/or controversial therapies for preterm infants and enhances research capacity.
The Preclinical Intensive Care Research Unit or PICRU, is an exciting new nationally collaborative facility for evaluation of long-term outcomes of emerging fetal and neonatal treatments. The PICRU will be based in the Large Animal Facility at UWA, operating 24 hours/day for 7 days a week during study periods. The resource intensive nature of the studies makes optimization of research outcomes an imperative. Extensive tissue sampling and opportunities for longitudinal physiological recordings offer possibilities for collaborative gain. The PICRU will be staffed by paid undergraduates, enhancing the teaching-research nexus, and offering early exposure to the research environment. Initial funded studies commencing in September 2014 will target the neurodevelopmental and cardiorespiratory outcomes of postnatal steroids and ventilation strategy in the developing preterm lamb, and how these outcomes are influenced by an antenatal inflammatory stimulus.
Professor Jane Pillow, School of Anatomy, Physiology & Human Biology, UWA
Room 1.81, Anatomy, Physiology & Human Biology buiding north
: 6488 3313
Tue, 25 Mar 2014 13:00
Tue, 25 Mar 2014 14:00
Debbie Hull <[email protected]>
Tue, 10 Feb 2015 15:25
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