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SEMINAR: Vascular retinopathy: A specific role for IGF-I?

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Today's date is Saturday, January 16, 2021
Vascular retinopathy: A specific role for IGF-I? Other events...
Diabetes affects more than 300 million people worldwide and is expected to affect 500 million persons by 2030. Diabetic retinopathy is considered as a specific microvascular complication of diabetes, and remains the leading cause of blindness in working-aged people. Microvascular changes serve as the basis for the classification of diabetic retinopathy into non-proliferative and proliferative phases. Non-proliferative diabetic retinopathy is characterized by a group of vasodegenerative lesions, such as thickening of capillary basement membrane, pericyte and vascular smooth muscle cells dropout, capillary occlusion and formation of microaneurysms. In the proliferative phase, as a consequence of increasing retinal ischemic-driven secretion of cytokines and growth factors, retinal neovascularization occurs. By means of mouse models we have studied the role of IGF-1, both during non-proliferative and proliferative retinopathy.

Jes˙s Ruberte is Chair Professor of Veterinary Anatomy at the Facultat de VeterinÓria, Universitat Aut˛noma de Barcelona, Spain. He obtained his Veterinary Degree in 1982 and a PhD in Veterinary Anatomy in 1987. His research interest is Retinopathy in mouse models and he has published many papers in this area.
Speaker(s) Jes˙s Ruberte
Location Seminar Rm 1.81, Anatomy Physiology and Human Biology
Contact Debbie Hull <[email protected]>
Start Tue, 16 Jul 2013 13:00
End Tue, 16 Jul 2013 14:00
Submitted by Debbie Hull <[email protected]>
Last Updated Fri, 12 Jul 2013 15:05
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