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SEMINAR: Developing therapies for age-related muscle wasting - sarcopenia

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Today's date is Friday, May 07, 2021
Developing therapies for age-related muscle wasting - sarcopenia : School of Anatomy, Physiology & Human Biology Seminar Series Other events...
The Seminar: With ageing, the progressive loss of skeletal muscle mass and function (sarcopenia) results in frailty, loss of independence and is a major cause of increased falls and fractures. Surprisingly little is known about the mechanisms of sarcopenia and these will prove to be complex. We have established a mouse model of sarcopenia and described the time course of age-related muscle wasting in C57Bl/6J mice. This model is currently used to investigate mechanisms of age-related muscle wasting. The talk will focus on three aspects of sarcopenia: 1) understanding molecular changes in ageing muscle with the aim to identify sarcopenia markers and develop therapies; 2) loss of myofibre innervation; 3) use of exercise as an intervention to prevent sarcopenia.

The Speaker: Tea Shavlakadze is a Research Associate Professor at the School of Anatomy, Physiology and Human Biology, the University of Western Australia. The research of TS has targeted factors controlling growth and maintenance of skeletal muscle mass and potential therapies for muscle disorders with a focus on in vivo studies using mouse models. Major areas of research include the role of Insulin-like Growth Factor-1 (IGF-1) in regulating skeletal muscle mass, and analyses of signalling pathways and other factors involved in many situations of skeletal muscle wasting.

Speaker(s) Research Associate Professor Tea Shavlakadze - School of Anatomy, Physiology & Human Biology, UWA
Location Room 1.81, Anatomy, Physiology & Human Biology Building North
Contact Debbie Hull <[email protected]> : 6488 3313
Start Tue, 13 Nov 2012 13:00
End Tue, 13 Nov 2012 14:00
Submitted by Debbie Hull <[email protected]>
Last Updated Tue, 30 Oct 2012 15:55
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