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SEMINAR: “Antisense oligomer therapies for neuromuscular disorders”

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Today's date is Monday, October 19, 2020
“Antisense oligomer therapies for neuromuscular disorders” Other events...
Sue Fletcher completed her first degree at the University of Zimbabwe (when the country still had a functional education system) and a PhD at UWA. She is a Principal Research Fellow working with Steve Wilton on developing antisense therapies for inherited disorders at the Centre for Neuromuscular and Neurological Disorders, University of Western Australia. The Wilton laboratory is located within the Australian Neuromuscular Research Institute, which is also the home of Muscular Dystrophy Western Australia. This group pioneered antisense oligomer induced exon skipping to overcome dystrophin mutations, and have developed antisense oligos for every dystrophin exon, except the first and last. Although not all dystrophin mutations are amenable to exon skipping intervention, and the potential improvements will depend upon the nature and location of the mutation, oligomer strategies should be developed for all, not just those with common mutations. The group are now exploring ways to overcome DMD-causing non-deletion mutations, including duplications and extending the technology to other inherited neuromuscular disorders, including spinal muscular atrophy.
Speaker(s) Susan Fletcher
Location Bruce Hunt Lecture Theatre, Level 2 South Block, Royal Perth Hospital (Enter South Block directly from Wellington Street, at street level, and the theatre is on your immediate right.)
Contact Fiona Mackenzie <[email protected]> : 93463838
URL https://www.waimr.uwa.edu.au
Start Wed, 24 Oct 2012 16:00
End Wed, 24 Oct 2012 17:00
Submitted by Fiona Mackenzie <[email protected]>
Last Updated Fri, 19 Oct 2012 14:30
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