SEMINAR: "Investigation of the mechanisms and regulation of RNA binding by the paraspeckle proteins as a route to deciphering paraspeckle function". AND "Investigating the induction mechanism of a long non-coding RNA: NEAT1, and paraspeckles.”
|"Investigation of the mechanisms and regulation of RNA binding by the paraspeckle proteins as a route to deciphering paraspeckle function". AND "Investigating the induction mechanism of a long non-coding RNA: NEAT1, and paraspeckles.”
Ellen completed a Bachelor of Science at the University of Western Australia in 2009. Following this she did Honours in the lab of Professor Charlie Bond (BBCS, UWA). After completing Honours, Ellen did an Internship at the University of Queensland in Professor John Mattick’s lab, a world leader in the field of non-coding RNA research. Ellen then started her PhD at WAIMR in the lab of Dr Archa Fox and is currently in her second year.
Ellen’s PhD project involves investigating the interactions occurring within paraspeckles: an RNA:Protein sub-compartment located in mammalian cell nuclei. This project aims to perform the first detailed analysis of the interactions between the paraspeckle proteins and the RNAs they bind, with the aim of one day utilizing this information to target lncRNA:protein complexes as therapeutic targets.
Ruohan Li finished his undergraduate degree with Honours in biomedical science in UWA. During his Honours and a voluntary research year in the same lab, he worked under Dr. Thomas Martin on the protein-protein interactions and stress responses mediated by 14-3-3 proteins. He then started his PhD with Dr. Archa Fox in April 2011 on a project aimed at investigating the induction mechanism of a 23kb long non-coding RNA called NEAT1 (Nuclear Enriched Abundant Transcript 1). This work seeks to provide insights into the unknown physiological function of paraspeckles, by understanding how NEAT1 is regulated in a variety of normal and diseased cell types.
Ellen Fortini & Ruohan Li
Bruce Hunt Lecture Theatre, Level 2 South Block, Royal Perth Hospital (Enter South Block directly from Wellington Street, at street level, and the theatre is on your immediate right.)
Wed, 23 May 2012 16:00
Wed, 23 May 2012 17:00
Fiona Mackenzie <[email protected]>
Fri, 11 May 2012 11:20
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