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SEMINAR: CMCA Seminar Series - Todays Forecast: Be prepared for “An Influx™ of clones!”

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Today's date is Monday, November 30, 2020
CMCA Seminar Series - Todays Forecast: Be prepared for “An Influx™ of clones!” : T cells are the shock troops of the human immune system – Other events...
T cells are the shock troops of the human immune system – they can be ordered to kill what they recognise. Remarkably nearly every T cell is uniquely different to each other due to mutations that occur during the synthesis of their T cell receptor (TCR). It is the highly specific binding of a T cell receptor to a molecular shape expressed on the surface of other cells, that mediates their function. To study the development and specificity of an immune response to a new immune target we are endeavouring to determine the structure of the TCR's of the T cells involved. This talk will describe the approach taken to select the reactive T cells from a donor's blood cells and then grow from them clones. In the process amplifying in culture a single T cell into a bulk population of millions, thus enabling subsequent sequence analysis and functional assays.
Speaker(s) Dr Andrew Lucas (Institute for Immunology and Infectious Dieseases, Murdoch University)
Location CMCA Seminar Room, Fairway Entrance #2 Physics Building, 1st floor
Contact CMCA Admin <[email protected]> : 64888098
URL https://www.cmca.uwa.edu.au/
Start Thu, 24 Nov 2011 16:00
End Thu, 24 Nov 2011 17:00
Submitted by CMCA Admin <[email protected]>
Last Updated Wed, 16 Nov 2011 16:03
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