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SEMINAR: Microbiology & Immunology Seminar Series: Helicobacter pylori outer membrane vesicles: biogenesis and protein sorting

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Today's date is Thursday, January 21, 2021
Microbiology & Immunology Seminar Series: Helicobacter pylori outer membrane vesicles: biogenesis and protein sorting : PhD proposal Other events...
Ms Tingting Liao will give a talk on "Helicobacter pylori outer membrane vesicles: biogenesis and protein sorting" in the Microbiology & Immunology Discipline Seminar room, Friday, 21 October 2011 at 9:00am. The release of outer membrane vesicles (OMVs) is conserved among Gram-negative bacteria, including many pathogens, such as Neisseria meningitidis, Pseudomonas aeruginosa, Helicobacter pylori, etc. These vesicles are spherical, bilayered proteolipids and 20-300nm in size. Although bacterial OMVs have long been studied, the mechanisms by which Gram-negative bacteria shed OMVs and sort vesicle-targeted proteins have not been fully determined. Helicobacter pylori is a Gram-negative bacterium which infects more than half of the global population. Infection is generally life-long due to the inability of the immune system to clear the bacteria from the gastric niche. Existing data have suggested that the release of H. pylori vesicles is an important mechanism of H. pylori virulence for delivery of molecules to host cells for modulation of host-pathogen interactions. This research proposal aims to study the biogenesis and protein sorting mechanism of H. pylori OMVs. Finally, the identification of signals or mechanisms of protein sorting during OMVs biogenesis could enable the engineering of H. pylori vesicles decorated with specific antigens for production and/or delivery of vaccines.
Speaker(s) Ms.Tingting Liao
Location Seminar Room 1.1, 1st Floor L Block, QEII Medical Centre
Contact Olga Eley <[email protected]> : 9346 2245
Start Fri, 21 Oct 2011 09:00
End Fri, 21 Oct 2011 09:45
Submitted by Gillian Walters <[email protected]>
Last Updated Thu, 13 Oct 2011 14:11
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