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SEMINAR: Mechanisms of T cell extravasation into the CNS

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Today's date is Friday, March 29, 2024
Mechanisms of T cell extravasation into the CNS : School of Anatomy & Human Biology Seminar Series Other events...
The Seminar: The seminar will deal with the mechanisms used by T lymphocytes to penetrated CNS postcapillary vessels, studied using a murine model of experimental autoimmune encephalomyelitis (EAE). The focus of the talk will be the interplay between cytokines (TNF-, IFN- and IL-17), the gelatinases (MMP-2 and MMP-9) and chemokines in establishing a chemotactic signal attracting T lymphocytes into the CNS parenchyma.

The Speaker: Lydia Sorokin obtained her PhD from the Physiology Department at the University of Western Australia in receptor-mediated endocytosis and carried out her first postdoctoral position at the Friedrich-Miescher laboratory of the Max-Planck Society in Tübingen, Germany, where she commenced her work on the extracellular matrix. She has spent the last 22 years in Germany and Sweden and is currently professor and director of Pathobiochemistry at the Westfälische Wilhelms University in Münster, Germany. Her interests are the biochemistry, ultrastructure and function of basement membranes, with an emphasis on vascular basement membranes and inflammation, and the role of the ECM in secondary lymphoid organs.

Speaker(s) Professor Lydia Sorokin, C4 Professor (Chair) of Physiological Chemistry and Pathobiochemistry, Muenster University, Muenster, Germany
Location Anatomy & Human Biology Building, 1st Floor Seminar Room (Rm 1.81)
Contact Debbie Hull <[email protected]> : 6488 3290
Start Tue, 08 Mar 2011 13:00
End Tue, 08 Mar 2011 14:00
Submitted by Debbie Hull <[email protected]>
Last Updated Mon, 21 Feb 2011 09:58
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