SEMINAR: "Towards understanding the molecular basis for multiple G protein coupling of GPCRs�
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"Towards understanding the molecular basis for multiple G protein coupling of GPCRs� |
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Akli obtained his PhD at the Cochin Institute (Paris, France) in 2003 and during this period was instrumental in the development of the BRET technique and its application to study G protein-coupled receptors (GPCRs). Akli’s work on the homo- and heterodimerisation of melatonin receptors published in 2002 was one of the world’s first studies using BRET. Then, he moved to Jean Philippe Pin's laboratory (Montpellier, France) for his first postdoctoral position, researching the development of the TR-FRET technology and its combination with BRET to monitor the GPCR-G protein interaction in live cells. Akli then joined Kevin Pfleger’s group at WAIMR in August 2009.
Akli’s seminar will focus on his recent work using the TR-FRET and BRET techniques to investigate the multiple coupling of one GPCR (protease-activated receptor 1) to different G proteins and β-arrestins.
Speaker(s) |
Dr Aki Ayoub
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Location |
WAIMR Seminar Room, Ground Floor, B Block, SCGH, Hospital Ave Nedlands 6009
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Contact |
Fiona Mackenzie
<[email protected]>
: 9346 3838
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URL |
http://www.waimr.uwa.edu.au
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Start |
Wed, 24 Mar 2010 16:00
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End |
Wed, 24 Mar 2010 17:00
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Submitted by |
Fiona Mackenzie <[email protected]>
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Last Updated |
Mon, 22 Mar 2010 11:09
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