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SEMINAR: Bayliss Seminar Series

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Today's date is Friday, March 29, 2024
Bayliss Seminar Series : Combining Chemistry and Biology to Target Parasitic Infections Other events...
Selective drug delivery in parasitic and bacterial infections is a cornerstone of medicinal chemistry. There have been entire drug research programmes that have been shut down due to toxicity issues that have arisen from non-selective targeting and drug delivery. However, drug treatment has a number of associated problems, including the development of drug resistant parasites, poor drug efficacy against some parasite species and life-cycle stages, and side-effects on host cells due to non-selective drug delivery. Development of new drug classes is prohibitively expensive in both time and money, and there is therefore an increase in research aimed at prolonging the lifespan and effectiveness of current drugs. We have developed a set of tuneable vehicles able to deliver selectively both small molecular weight compounds as well as large biomolecules into nematodes, kinetoplastids and the intracellular stages of apicomplexan parasites. Our delivery vehicles can be easily generated and do not target uninfected mammalian cells, and as such, are non-toxic.
Speaker(s) Rudi Marquez, Department of Chemistry, Xi'an Jiaotong-Liverpool University
Location Bayliss Building, G33
Contact The School of Chemistry and Biochemistry Team <[email protected]> : 6488 4402
Start Fri, 26 Aug 2016 12:00
End Fri, 26 Aug 2016 12:45
Submitted by scbevents <[email protected]>
Last Updated Tue, 09 Aug 2016 14:37
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