SEMINAR: HCV adaptation to host immune responses during acute infection: relevance to infection and treatment outcomes

Hepatitis C virus (HCV) infection is a global health problem with an estimated 170 million people infected worldwide presenting a risk to develop end-stage liver diseases such as cirrhosis and liver cancer. Albeit the host’s immune responses developed against HCV and/or initiation of treatment aid in controlling the infection, the virus uses its plasticity and propensity to develop viral adaptations as an escape strategy to impair the host’s immune responses and compromise treatment efficacy thus resulting in chronic infection for the majority of people exposed to the virus. Understanding viral escape dynamics in HCV infection is of primary importance for effective drug and vaccine design.

Biography,

Anne Plauzolles, currently a PhD student at the Forensic Centre at UWA. Ten years ago, she started to study molecular and cellular biology at the Faculty of Science in Montpellier. After obtaining her bachelor degree, she then undertook a Diploma of criminal sciences in the faculty of law in the same city. In 2006, she moved to Australia and continued her study at UWA with a diploma of forensic sciences. Following this diploma Anne specialised in virology through the study of HCV along with her master and current PhD.

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****All Welcome****