SEMINAR: �Paraspeckles � an emerging model system for studying long noncoding-RNA protein complexes in gene regulation�

Dr. Archa Fox is a group leader at WAIMR. She completed her PhD with Professor Merlin Crossley at the University of Sydney, studying the interaction between hematopoietic transcription factors. She then went on to Post-Doc with Professor Angus Lamond at the University of Dundee, where she carried out research on subnuclear organisation, discovering new subnuclear structures termed 'paraspeckles'. Archa and her group use a range of different cellular and molecular biology techniques in order to study paraspeckle structure and function. She focuses on RNA-based methodology, particularly the challenges of working with long noncoding RNAs, and also couples this with fluorescence microscopy and biochemistry. This seminar will encapsulate the research over the last 3-4 years in Archa's laboratory, in collaboration with several other groups including that of her husband, Charlie Bond, a structural biologist at UWA.