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SEMINAR: Natural compounds as inhibitors of the 10 hallmarks of cancer

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Today's date is Sunday, December 15, 2019
Natural compounds as inhibitors of the 10 hallmarks of cancer : School of Anatomy, Physiology & Human Biology Raine Lecture Other events...
Marc Diederich was awarded his PhD in molecular pharmacology in 1994 by the University Henri Poincaré Nancy 1, France. After training at the University of Cincinnati, USA, he focused his research on cancer and leukemia cell signaling pathways and gene expression mechanisms triggered by natural compounds with epigenetic-, anti-inflammatory- and cell death-inducing potential. Professor Diederich directs the Laboratory for molecular and cellular biology of cancer (LBMCC) at Kirchberg Hospital in Luxemburg. In 2012 he was appointed Associate Professor of Biochemistry at the College of Pharmacy of Seoul National University. Since 1998, he has been the organizer of the “Signal Transduction” meetings in Luxembourg. Professor Diederich’s research focuses on the development of novel anti-cancer drugs,for example, natural marine compounds which represent an interesting source of novel leads with potent chemotherapeutic or chemo-preventive activities. In the last decades, structure-activity-relationship studies have led to the development of naturally-derived or semi-synthetic analogues with improved bioactivity, a simplified synthetic target or less toxicity. Professor Diederich and his collaborators investigated for example chalcones that are aromatic ketones, known to exhibit anti-microbial, anti-inflammatory and anti-cancer activities. Organic sulfur compounds (OSCs) derived from plants, fungi or bacteria can also serve as chemopreventive and/or chemotherapeutic agents and attracted Professor Diederich’s interest as a promising source for novel anti-cancer agents.
Speaker(s) Raine Visiting Professor Marc Diederich, College of Pharmacy, Seoul National University, Korea & Laboratoire de Biologie Moleculaire et Cellulaire du Cancer, Hopital Kirchberg, Luxembourg
Location Room 1.81, Anatomy, Physiology & Human Biology (north)
Contact Professor Arun Dharmarajan <arunasalam.dharmarajan@uwa.edu.au> : 6488 2981
Start Tue, 15 Jan 2013 13:00
End Tue, 15 Jan 2013 14:00
Submitted by Debbie Hull <debbie.hull@uwa.edu.au>
Last Updated Fri, 11 Jan 2013 21:39
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